Talkeetna is located at the confluence of three rivers, the Susitna, Chulitna and Talkeetna. Flightseeing, rafting, mountain biking, hiking, camping, fishing and hunting make up a large portion of the local economy. Talkeetna is a 2½-hour drive from Anchorage, the largest city in Alaska. The core downtown area (Talkeetna Historic District) is on the register of National Historic Places, with buildings dating from the early 1900s including Nagley’s General Store, Fairview Inn and the Talkeetna Roadhouse.
The climate is continental subarctic, assuming some characteristics like warm-summer but the shorter duration of the hot season and long winters give the town boreal features and in terms of vegetation is composed of taiga (Cook Inlet Basin), different from the southcentral coastal more diversified. Even though the cold, dry air comes from the north, the moisture acquired comes from the Gulf of Alaska. That is, summers are between a short duration and an average duration.
The Moose Dropping Festival, a two-day celebration held each July, came to an end with the announcement on August 21, 2009, by the Talkeetna Historical Society that the festival has been canceled. The event was named after a lottery where participants bet on numbered, varnished pieces of moose feces, or „moose droppings“ dropped from a helicopter onto a target. A softball tournament historically has been held on the same weekend as the Moose Dropping Festival but is not part of the festival itself. Other events that typically held on Moose Dropping Festival weekend included a five-kilometre walk-run—also not a part of the official festival, a Mountain Mother contest, and a parade.